Site Contacts

Marjorie Guzman, BHS – CEO

Marjorie established TOPAZ Clinical Research in 2016 after acquiring over 18 years of experience in clinical research at the site level, university level, and Sponsor level. Marjorie has experience as a study coordinator, certified rater, regulatory analyst, and 14 years as a Clinical Research Associate (CRA) in various therapeutic areas.  She knows the finest details required to efficiently oversee a successful research site, that is evident to sponsors that continually return to TOPAZ Clinical Research to fulfill their study needs.



Kristi Boone, R.N.  – Lead Study Nurse Coordinator/Business Development

Kristi is a  registered nurse with over 12 years of  experience in various positions, including years in the Neonatal Intensive Care Unit, and Emergency room. Kristi has 2 years of clinical research experience with TOPAZ Clinical Research, and with her years of excellent bedside manner and diligent collection of data, she is a great addition to the TOPAZ Clinical Research team. She has the ability as an experienced study coordinator and nurse to conduct various clinical procedures from infant to adult, recruit, maintain patient retention and compliance, collect quality data, and always keep the lines of communication open with patients and sponsors.

Certified in ACLS, BLS, PALS, Certified Child Passenger Safety Technician and Instructor, American Heart NIH Stoke Certified, Experienced as a lactation nurse.



Karla Francisco, BA – Director of Operations/Business Development

Karla has years of experience in administrative and managerial positions successfully leading large teams in daily operations and projects. Karla has 7 years of experience in clinical research in various administrative positions, and her expertise at TOPAZ Clinical Research includes, but are not limited to, managing operations,  project management, contracts and budgets, and business development. At TOPAZ Clinical Research, Karla is the go to person for all daily operations.



At TOPAZ Clinical Research, our team includes study Coordinators, Certified Raters, Regulatory Specialists, Business Development Department, Patient Recruitment Coordinators, and Investigators with various specialties. Everyone is GCP Certified, and selected individuals are also IATA Certified. TOPAZ Clinical Research provides unsurpassed education/certifications for all employees.

BLS, ACLS, PALS, GCP, IATA certified staff. 

Bilingual staff- English/ Spanish.

If you are a Sponsor, please contact

Contact Us

TOPAZ Clinical Research 
2513 E. Semoran Blvd. 
Apopka, FL 32703

Phone: 407-703-4342
Fax: 321-256-5416


      TOPAZ Clinical Research has an experienced and talented team with investigators with various specialties.

  • Dr. Gutierrez is the Principal Investigator for all pediatric studies at TOPAZ Clinical Research. She has a large range of research experience working with newborns to young adults, and is the primary care physician for TOPAZ Pediatrics opening September 2020.

  • Family Practice Principal Investigator has a private practice and clinical research experience in  20+ trials in various therapeutic areas including dermatological studies, Cardiac studies, CNS studies, Mood disorder studies, and Psychiatric studies.

  • Emergency Medicine Principal Investigator has over six years in Clinical Research, and has completed over 60+ studies of Alzheimer’s disease, Parkinson’s disease, Depression, Anxiety, Diabetes, and other therapeutic areas.

  • Forensic and General Psychiatry Principal Investigator is a knowledgeable and experienced psychiatrist. Our Investigator is also a speaker for past and present pharmaceutical companies.

  •  Dental Surgery Principal Investigator is well known in our area and has a large practice with availability to the most modern devices; right next door to TOPAZ Clinical Research.

  • Sub- Investigators- Physician Assistant with years of experience in all phases of research. In addition, we have an extensive database of experienced Medical Physicians with a broad range of specialties that can fill the need of any therapeutic area.